In physiotherapy, there is a gap in the practice and delivery of evaluation and treatments for persistent musculoskeletal pain. Various psychosocial factors, according to evidence, have a role in persistent musculoskeletal pain. Today’s physiotherapy sessions, on the other hand, are mostly biomedical in character, with psychosocial issues receiving minimal consideration. However, global trends in chronic musculoskeletal pain management techniques have shifted to a multidimensional bio psychosocial approach that is comprehensive, holistic, and patient-centered. Treatment sessions are integrated with patient-centered biopsychosocial interactions, and a comprehensive clinical biopsychosocial examination is recommended. Physiotherapists may benefit from adding general self-management programmes and pain neuroscience into their practises, as well as exercise prescription that takes into consideration both the patient’s needs and the clinician’s ability. Furthermore, physiotherapist prescription behaviour must alter and comply with current pain management recommendations and standards, and physiotherapists should regard their Competencies as superior management tools in patient-centered physiotherapy treatment regimens.